Retinoblastoma examination

Retinoblastoma - Diagnosis and treatment - Mayo Clini

Tests and procedures used to diagnose retinoblastoma include: Eye exam. Your eye doctor will conduct an eye exam to determine what's causing your child's signs and symptoms. For a more thorough exam, the doctor may recommend using anesthetics to keep your child still. Imaging tests Because a complete examination for retinoblastoma can be difficult for babies and young children, your doctor may recommend an Examination Under Anesthesia (EUA) as the best way to thoroughly examine your child's The EUA, may involve the following procedures: External examination of both eye Before the initial eye examination, your child may need a MRI or CT of the brain and orbits (eye sockets), with and without contrast (dye). These tests help to confirm the diagnosis of retinoblastoma and look for involvement of retinoblastoma with the optic nerve and any cancer outside of the eye Most common intraocular malignancy in children. 90% of all retinoblastoma cases are diagnosed by 3 years of age. Disease can be unilateral or bilateral. Most common presenting sign is leukocoria (white papillary reflex), which can often be seen in photographs. In 30% to 40% of cases, the disease.


  1. ation under anesthesia. An exa
  2. Cytologic and biopsy specimens are rarely obtained from eyes with suspected retinoblastoma owing to the potential risk of tumor seeding. An anterior chamber paracentesis may be performed, if indicated by clinical findings, and is not associated with risk of tumor seeding.1,
  3. ation. Retinoblastoma classically presents with single or multiple nodular, white or cream-colored masses often with pro
  4. ation: grayish white, vascularized retinal tumor; Following fundus exa
  5. ation is used to diagnose retinoblastoma, childhood cataracts, and other ocular abnormalities. Vision screening in children is an ongoing process with different components..
  6. Retinoblastoma, a neuroblastic tumor, is the most common primary intraocular malignancy of childhood. Patients usually present with leukokoria (white reflex or white pupil), detected in primary..

Retinoblastoma: DIAGNOSIS - Eye Cancer M

Infants or children in whom parents or other observers describe a history suspicious for the presence of leukokoria (a white pupil reflex) in 1 or both eyes should be examined by an ophthalmologist who is experienced in the examination of children, because small retinoblastoma tumors or other serious lesions may present in a subtle fashion Some children with retinoblastoma present with strabismus (lazy eye). All children with strabismus should be evaluated through a dilated eye exam for retinoblastoma. Due to a strong inherited component, screening examinations are recommended for all siblings and offspring of those patients with a history of retinoblastoma (see below) Retinoblastoma is a disease in which malignant (cancer) cells form in the tissues of the retina. Children with a family history of retinoblastoma should have eye exams to check for retinoblastoma. Retinoblastoma occurs in heritable and nonheritable forms Macroscopic and funduscopic examination reveals a white elevated mass with fine surface vessels 4. Histology. Histology demonstrates a small round-cell tumor of neuroepithelial origin. Flexner-Wintersteiner rosettes (relatively specific for retinoblastoma) and Homer-Wright pseudorosettes (also found in other PNETs) may be seen on microscopy

There is no international consensus regarding screening of children with a family history of retinoblastoma. Children at high risk may be screened up to every 2 weeks for the first 8 weeks of life, followed by monthly examinations during the first year. Screening may be performed in the clinic or under anaesthesia In the developed world, retinoblastoma is an uncommon yet highly curable ocular malignancy of childhood affecting 40-50 children in the UK each year. The presenting signs, most commonly leukocoria and squint, should alert the primary care physician or secondary care physician to examine for the red Diagnosis of retinoblastoma. Diagnosis is the process of finding out the cause of a health problem. Diagnosing retinoblastoma usually begins with a visit to your child's doctor. The doctor will ask you about any symptoms your child has and do a physical exam. Based on this information, the doctor may refer your child to a specialist or order. Rarely, children with retinoblastoma may experience pain, redness or swelling of one or both eyes. How is retinoblastoma diagnosed? In addition to a complete medical and physical examination, diagnostic procedures for retinoblastoma may include a thorough eye examination, medical history, genetic testing and an examination under anesthesia The interval between examinations may then be gradually increased to one examination every three months, even in case of unilateral retinoblastoma (because of the risk of late bilateral involvement) . The objective is to detect new tumors and ocular complications related to treatment

Background Early diagnosis strategies and advances in retinoblastoma (Rb) management have resulted in nearly 100% survival. More attention should, therefore, be given to quality of life considerations. We aimed to quantify the number of examinations under anaesthesia (EUAs) in a cohort of patients with Rb, as a measure of disease burden Preferred examination. The volume of the intraocular tumor is estimated by means of orbital A and B scanning and/or a computed tomography (CT) scanning. On rare occasions, RB is discovered during a well-baby examination. Most often, a parent first detects the symptoms of RB Neuromuscular examination of patients with retinoblastoma is usually normal. Extremities Simian crease in the palms and a broad thumb may be present in 13q deletion syndrome Retinoblastoma Malignant neoplasm of neurosensory retina almost exclusively affecting young children . Tumor Site (macroscopic examination / transillumination) (Notes ,ED) (select all that apply) ___ Superotemporal quadrant of globe ___ Superonasal quadrant of globe Eye examination. Intraocular retinoblastoma is usually diagnosed without pathologic confirmation. An examination under anesthesia with a maximally dilated pupil and scleral indentation is required to examine the entire retina. A very detailed documentation of the number, location, and size of tumors; the presence of retinal detachment and.

Retinoblastoma - History and exam BMJ Best Practic

Children diagnosed with retinoblastoma will require a complete physical examination. If there are any symptoms or abnormal findings, the child may also need additional tests to see if the cancer has spread to other parts of the body. Tests that may be performed include: Blood tests. Lumbar puncture Retinoblastoma is diagnosed by physical examination and classified as International Classification of Retinoblastoma groups A through E according to increasing severity. The most common presenting feature is a white pupillary reflex called leukocoria, often recognized first by parents. Strabismus and decreased vision are also common Retinoblastoma is a rare eye cancer found in children. It originates in the part of the eye called the retina. The retina is a thin layer of nerve tissue that coats the back of the eye and enables the eye to see. Most cases (about 60 percent) involve only one eye (unilateral), but in some children, both eyes may be involved (bilateral)

If you are not given a referral, ask where retinoblastoma is treated in your country, visit the One Retinoblastoma World Map, or contact us for advice. Watch a Red Reflex Eye Test. When There Is No Ophthalmoscope. For optimal examination of children's eyes, the Red Reflex Test will be performed with an ophthalmoscope. However, many primary. Retinoblastoma: An overview. Indian Journal of Pediatrics, 2012. Anish Ray. Download PDF. Download Full PDF Package. This paper. A short summary of this paper. 37 Full PDFs related to this paper. Read Paper. Retinoblastoma: An overview There are several different procedures doctors can use to diagnose retinoblastoma, including: Funduscopic eye exam: The patient is anesthetized and the pupils dilated so the retina can be examined. Ultrasound of the eye. Magnetic resonance imaging (MRI) scan. Blood tests. DNA and/or genetic testing Retinoblastoma is a unique neoplasm in that the genetic form imparts a predisposition to developing tumor in an autosomal dominant fashion with almost complete penetrance (85% to 95%). 16 The majority of such children acquire the first mutation as a new germline mutation, with only 15% to 25% having a positive family history. However, some families display an inheritance pattern characterized.

Retinoblastoma is the most common pediatric ocular tumour. It may rarely present in adults. The present case adds to the number of 26 cases already published in literature since 1919 till 2013. Our aim is to highlight the rare occurrence of retinoblastoma in adults along with its features which differentiate it from paediatric retinoblastoma Some of the tests for retinoblastoma include: examination of the eye using a light and magnifying glass (ophthalmoscopy) ultrasound of the eye. A wand like probe glides over gel that is placed on the outside of your child's eyelid. The probe uses sounds waves to form a picture of the eye and its structures on the scree

Retinoblastoma - EyeWik

In addition to a complete medical and physical examination, diagnostic procedures for retinoblastoma may include: Complete eye examination and medical history; Funduscopic examination. With the child under anesthesia, the pupils are dilated so the entire retina can be viewed and examined. Ultrasound exam of the eye Retinoblastoma (Rb) is an embryonal tumour of the retina and is the most common malignancy of the eye in children. Onset generally occurs between the third month of pregnancy and 5 years of age [].. Around 40% of retinoblastoma cases are caused by a hereditary mutation on chromosome 13, called the retinoblastoma 1 (Rb1) gene Retinoblastoma Diagnosis Retinoblastoma is easily confused with other less severe eye conditions, and careful examination is needed for accurate diagnosis. Many times an ophthalmologist may help with the examination, which is done in the operating room so that the entire retina can be examined

Purpose Current practice in retinoblastoma (Rb) has transformed this malignancy into a curable disease. More attention should therefore be given to quality of life considerations, including measures related to examinations under anesthesia (EUAs). We aimed to investigate EUA measures in bilateral Rb patients and compare the findings to EUAs in unilateral Rb. Methods A retrospective analysis of. Examinations under anaesthesia as a measure of disease burden in unilateral retinoblastoma: the London experience Ido Didi Fabian ,1,2,3 Vishal Shah, 1 Noa Kapelushnik,3 Zishan Naeem,2 Zerrin Onadim,2 Elizabeth Price,2 Tanzina Chowdhury, 2,4 Catriona Duncan,2, Initial exam raised concern for likely retinoblastoma. The patient was urgently taken for an exam under anesthesia, where fluorescein angiography demonstrated prominent feeder and drainage vessels, retinal vascular dilatation and telangiectasias, late vascular leakage, terminal vascular bulbs with extensive subretinal exudation, and prominent iris neovascularization with leakage (Fig. 2B, Fig.

  1. A specialized eye doctor called an ophthalmologist will conduct an eye exam as early as possible, even starting at birth, if there is a family history of retinoblastoma. Exams should then continue every one to two months during the first two years of life, and then less frequently as the child gets older
  2. ations for retinoblastoma over the past 100 years. When there is a family history of retinoblastoma, a child is most likely to develop the disease within 28 months of birth. Newborn babies should have a dilated eye exam by a pediatric ophthalmologist (eye doctor) in the nursery
  3. Absent red reflex or a white eye glow in dim light may be signs of serious eye disease in children, including retinoblastoma (cancer). A red reflex eye exam..

Retinoblastoma. Retinoblastoma is a cancer arising from the immature retina. Symptoms and signs commonly include leukocoria (a white reflex in the pupil), strabismus, and, less often, inflammation and impaired vision. Diagnosis is based on ophthalmoscopic examination and ultrasonography, CT, or MRI. Treatment of small cancers and bilateral. More than 75% of the eyes treated with two or more radiation treatments had a cataract removed. These results emphasize the importance of regular eye examinations for retinoblastoma survivors, particularly those who were treated with radiation. Chodick G, Kleinerman RA, Stovall M, Abramson DH, Seddon JM, Smith SA, Tucker MA The retinal examinations can be avoided if DNA testing indicates that the patient has a non-inherited form of retinoblastoma or if the sibling has not inherited the RB1 gene change/deletion. Any relatives who are found through DNA testing to have inherited an RB1 gene change/deletion should undergo the same surveillance procedures as siblings

The histopathological examination showed that the tumors were present in all of the rabbits which received the subretinal injection. The rabbit model demonstrated similar fundus appearance and pathologic features to human retinoblastoma At diagnosis tumours are usually vascular on Doppler examination. The vitreous may have multiple areas of 'floating' debris, which may represent vitreous seeding or alternatively necrotic debris, hemorrhage or increased globulin content. 43. RETINOBLASTOMA. 44. Retinoblastoma: Large tumor as seen in a 3D ultrasound block demonstrates calcium. Hereditary retinoblastoma also tends to occur in both eyes, as opposed to just one eye. Complications. Children treated for retinoblastoma have a risk of cancer returning in and around the treated eye. For this reason, your child's doctor will schedule follow-up exams to check for recurrent retinoblastoma A retinoblastoma is a malignant tumor of the retina, which is the thin sensory membrane at the back of the eyeball. It occurs as a result of a mutation in both copies of the RB1 gene that produces.

Retinoblastoma Diagnostic Testing and Surgery After a careful history and physical examination, we typically obtain:? MRI of the eyes and brain; an eye exam under anesthesia by the opthalmologist (biopsy of the tumor is not necessary if it has the classic appearance of a retinoblastoma) blood tests to measure blood counts and liver and kidney. To determine the ability to detect simulated retinoblastoma by using the red-reflex test. Discs that simulated retinoblastoma lesions were affixed to the retina of model eyes with an 8- or 3-mm pupil Retinoblastoma is the most frequent neoplasm of the eye in childhood, and represents 3% of all childhood malignancies. It is a cancer of the very young; two-thirds are diagnosed before 2 years An examination under anesthesia with a maximally dilated pupil and scleral indentation is required to examine the entire retina. A ver Retinoblastoma (Cancer of the Eye) Retinoblastoma is a rare type of cancer that grows on the retina at the back of the eye. It develops in children under age 5. Treatments include cryotherapy (freezing the tumor), chemotherapy and surgery. The prognosis depends on several factors, including whether cancer has spread to other parts of the body A diagnosis for retinoblastoma is never made by a biopsy when the tumor is confined to the eye or eyes. The diagnosis of retinoblastoma is made after a detailed examination of the affected eye or eyes by an experienced ophthalmologist. This section describes options for diagnosing retinoblastoma

Global Retinoblastoma Study Group, Fabian ID, Abdallah E, Abdullahi SU, Abdulqader RA, Adamou Boubacar S, et al. Global retinoblastoma presentation and analysis by national income level. JAMA. Retinoblastoma is a rare form of cancer that rapidly develops from the immature cells of a retina, the light-detecting tissue of the eye. It is the most common malignant cancer of the eye in children, and it is almost exclusively found in young children. The most common and obvious sign of retinoblastoma is leukocoria The International Council of Ophthalmology (ICO) represents and serves professional associations of ophthalmologists throughout the world. The International Council of Ophthalmology works with ophthalmologic societies and others to enhance ophthalmic education and improve access to the highest quality eye care in order to preserve and restore vision for the people of the world

Retinoblastoma is a heritable pediatric cancer driven by mutations in RB1. Four samples were obtained by skin biopsy at the time of anesthesia for examination of the eyes as part of routine. Retinoblastoma is a malignancy associated with somatic mutation or germline mutation [2, 4].Knudson proposed the two-hit hypothesis where he described the occurrence of two consecutive mutations for the conversion of a normal retinal cell into a malignant cell (Fig. 1).In heritable retinoblastoma, the first mutation is in the germ cell, and this 'first hit' is carried in every cell in the. Retinoblastoma is an aggressive eye cancer of infancy and childhood. Survival and the chance of saving vision depend on severity of disease at presentation. Retinoblastoma was the first tumour to draw attention to the genetic aetiology of cancer. Despite good understanding of its aetiology, mortality from retinoblastoma is about 70% in countries of low and middle income, where most affected. Retinoblastoma is a tumour which usually affects children aged under 5. Most commonly, it affects children aged under 2, including newborn babies. It is a tumour of the nerve layer of the retina, which is the light-sensitive membrane at the back of the eye. The tumour grows from the retina very early in its life, when it is still developing Retinoblastoma Definition Retinoblastoma is a malignant tumor of the retina that occurs predominantly in young children. Description The eye has three layers, the sclera, the choroid, and the retina. The sclera is the outer protective white coating of the eye. The choroid is the middle layer and contains blood vessels that nourish the eye. The front.

Retinoblastoma - The American Society of Retina Specialists

In the case of Retinoblastoma, early detection can save the child's life! The eye test is very important, but an evaluation with an eye doctor needs to be evaluated in the first 6 months and maximum in the first year of life of the baby! It is our role as a pediatrician to make parents aware that the eye test does not replace the eye examination Fundoscopy, ultrasound, and magnetic resonance imaging (MRI) are the examinations of choice in patients being investigated for retinoblastoma. Long answer Fundoscopy using an indirect ophthalmoscope is the optimum technique for identifying the lesion(s) and documenting the location and clinical characteristics Quellen. Temming et al.: Incidence of second cancers after radiotherapy and systemic chemotherapy in heritable retinoblastoma survivors: A report from the German reference center In: Pediatric Blood & Cancer. 2016, doi: 10.1002/pbc.26193 . | Open in Read by QxMD. Broaddus et al.: Survival with retinoblastoma in the USA: 1975-2004 In: The British journal of ophthalmology Retinoblastoma is a rare form of eye cancer that is most commonly found in children, but it can be detected easily with an eye exam. In many cases, the child is born with the condition, due to problems with the eye's development while in the womb. The good news is, retinoblastoma is one of the most commonly-treated and survivable of childhood. We were surprised to see that, in their Seminar on retinoblastoma (April 14, p 1436),1 Helen Dimaras and colleagues did not mention the red reflex test. Many published studies, including this Seminar, underline that leukocoria is mainly noticed by relatives of the affected children. In a study of 1831 children affected by retinoblastoma,2 leukocoria was noted by relatives in 1315 (80%) of the.

Retinoblastoma occurs due to mutation in RB1, a tumor suppressor gene, in retinal cells. If one sibling is affected, there is a 2% risk that another sibling will be affected. If parents are affected, there is 40% risk that a child will inherit it Red reflex examination for retinoblastoma. September 2012; The Lancet 380(9844):803; Retinoblastoma was the first tumour to draw attention to the genetic aetiology of cancer. Despite good. Retinoblastoma is a tumour of early childhood arising in the cells of the light sensitive lining of the eye known as the retina. In about two-thirds of children only one eye is affected but in one-third, tumours may develop in both eyes. Retinoblastoma is caused by a gene that controls the growth of cells in the eye Retinoblastoma is a cancer of the retina, a light-sensitive layer of tissue in the eye. Among children, it is the most common malignant tumor that starts in eye. Still, it is very rare, with only about 250 to 300 cases diagnosed each year in the United States. It usually occurs before age five, and most of these cases occur in children under two Siblings of a child with retinoblastoma should undergo molecular genetic testing, and if found to have a germline mutation, should undergo clinical examination every 3-4 weeks until the age of 1.

Photograph reveals Retinoblastoma in child's eye | CentralRetinoblastoma physical examination - wikidoc

Review of Retinoblastoma - American Academy of Ophthalmolog

Using the ophthalmoscope at arm's length, check for the bilateral red reflex (the reflection from the retina of the eye) to identify any congenital cataracts or retinoblastoma. Examination for the red reflex should be performed in a darkened room and the lens setting adjusted to bring the baby's eyes into focus (fig 2 ⇓) Examining the neurological system is different in young children compared with older children and adults. The components of the complete exam are extensive and usually cannot be performed in a classical fashion. This approach may be carried out on a cooperative school-aged child - but always be mindful of keeping the examination fun

Geeky Medics provides free medical student revision resources, including OSCE guides, clinical skills videos, clinical cases and quizzes (MCQs) basis of a clinical examination, ophthal-moscopy and ultrasound. Magnetic reso-nance imaging* (MRI) is the procedure of choice for visualizing the local ophthal-mic findings, the extent of the tumor and possible associated brain changes, Optimized Examination Technique Reduces Examination Time for Children with Retinoblastoma by Hal 4. ocular mass (retinoblastoma, melanoma) 5. strabismus. 6. What are 14 examples of systemic disorders in which examination of the fundus may be abnormal even without visual symptoms? Systemic hypertension 2. Malignant hypertension (hypertensive crisis) 3. Diabetes mellitus 4. Sickle cell disease 5

We report a case of a man aged 35 years who presented with the chief complaint of painless diminution of vision in the right eye for 4 months. Examination revealed a large inferior retinochoroidal mass along with retinal detachment. An anterior choroidal mass with moderate internal reflectivity was seen on B-scan ocular ultrasonography and MRI and CT scan were indicative of a mitotic aetiology Less common signs and symptoms of retinoblastoma include: Vision problems. Eye pain. Redness of the white part of the eye. Bleeding in the front part of the eye. Bulging of the eye. A pupil that doesn't get smaller when exposed to bright light. A different color in each iris (the colored part of the eye) If the cancer spreads outside the eye. Anyone who has been treated for retinoblastoma should have a careful examination by an ophthalmologist at least once a year to monitor for any possible complications. It's important to protect your eyes from further damage. Some ways to do this are: Wear sunglasses with UV protection when in bright sunlight A few days after surgery, the patient suffered a major vitreous hemorrhage and 1 month later the eye was enucleated. Histopathological examination of the globe revealed that nearly all the tumor tissue was necrotic. However, the vitreous contained some retinoblastoma cells that appeared viable

Intravenous Chemoreduction or Intra-arterial Chemotherapy

Retinoblastoma - Knowledge @ AMBOS

Retinoblastoma is caused by a mutation in a gene that controls how cells divide. As a result, cells grow out of control and become cancerous. In about half the cases, this mutation develops in a child whose family has never had eye cancer. In other cases, the mutation occurs in several family members. If the mutation runs in the family, there. The exam is organised by AIIMS Delhi which provides career opportunities in courses like MD/MS and also in a 6-year course of DM/MCh. The AIIMS PG exam is organised twice a year. The first attempt can be given in January and the second attempt in July. The tentative dates for AIIMS PG 2021 are as follows: Events

Childhood Eye Examination - American Family Physicia

The doctor will also examine the participant's eyes with the ophthalmoscope method. The results from both CRADLE and the ophthalmoscope method will be recorded and compared (white eye present versus absent, and normal versus abnormal as described above). STRATUM III - Infants and children receiving treatment for retinoblastoma Although retinoblastoma is a rare disorder, it is the most common cancer of the eye in children, accounting for about 3% of all childhood malignancies. Retinoblastoma affects males slightly more often than females. The incidence in the United States and Europe is estimated to be 2-5 children per 1,000,000 people in the general population The first step in diagnosing retinoblastoma is a preliminary eye exam, in which an eye doctor will assess your child's symptoms. The full diagnosis, however, will often involve multiple steps, including the following: An initial eye exam will be performed to determine what is causing any symptoms of retinoblastoma Inherited retinoblastoma has an autosomal dominant pattern of inheritance with 80-100% penetrance. Sporadic lesions usually result from spontaneous mutation . Diagnosis is typically by ophthalmologic examination, prompted by leukocoria or white reflex [1, 3] seen in 60% of patients Herein, we report a typical case of unilateral microphthalmos, which was clinically diagnosed as retinoblastoma but histopathological examination revealed retinal dysplasia. The parents of a 9-month-old child noticed a white reflex in the child's left eye since 6 months of age

And, because of the increased risk of cancer, later on, annual or bi-annual exams and screening tests are recommended to catch potential future cancers early on. Sporadic (non-heritable) retinoblastoma This type of retinoblastoma is also related to the RB1 gene, but the mutation is retina-specific. It accounts for 2/3rds of all retinoblastoma. Retinoblastoma is a type of eye cancer that affects the retina, the inner layer of the eye. Nerve cells in the retina sense light and send images to the brain and allow us to see. Retinoblastoma causes tumors (clumps of cells) to grow in the retina. This happens when the nerve cells grow out of control

Retinoblastoma - American Family Physicia

Retinoblastoma is cancer of the retina. The retina is the light-sensitive lining at the back of the eye. During the early stages of a baby's development, retinal eye cells grow very quickly and then stop growing. However, in rare cases, one or more cells continue to grow and form a cancer called retinoblastoma Conditions treated include eye misalignment, lazy eye, abnormal eye movements, droopy eyelids, glaucoma, cataracts, retinoblastoma and retinopathy of prematurity. Click here to see what an eye examination at the Royal Children's Hospital looks like. Tweet. Support us The Royal Children's Hospital Melbourne. Telephone +61 3 9345 5522.

Retinoblastoma - Pictures, Symptoms, Definition, TreatmentWhat PERRLA Means in Your Eye ExamEmployment at Illinois Eye Center - Peoria and Washington, IL

Retinoblastoma (RB) is the most common intraocular malignancy in childhood. Approximately 40% of retinoblastomas are hereditary and due to germline mutations in the RB1 gene. Children with hereditary RB are also at risk for developing a midline intracranial tumor, most commonly pineoblastoma. We recommend intensive ocular screening for patients with germline RB1 mutations for retinoblastoma as. The Colleges of Medicine of South Africa oversee the postgraduate specialisation of South African doctors. The CMSA offers examinations and regulates post graduate training in all medical specialisations. The website provides information about the different colleges, examinations, examination schedules, etc. and about the organisational structure of the CMSA The only way to find retinoblastoma tumor early is to examine the eye with specific expertise, which we cannot do for every child. The earliest signs of retinoblastoma detectable by parents are leukocoria (white pupil), either directly or in photographs (photo-leukocoria), and strabismus when the macula is involved by tumor Although a wide range of specimens may appear in the examination, a survey of candidates who sat the examination in the past five years shows some clear favorite topics. In this section, only the commonly encountered specimens are shown and discussed. If you like to contribute, please e-mail to this address chuaoxford@hotmail.co Even adult family members of a child with retinoblastoma need to have an eye examination. Even though adults will not develop retinoblastoma, the gene that causes retinoblastoma can also cause a noncancerous (benign) eye tumor called retinocytoma